Scientists have created the most comprehensive method yet to predict a woman’s risk of breast cancer, according to a study led by researchers at the University of Cambridge. The study, funded by Cancer Research, is published today in Genetics in Medicine. They have a developed a way of calculating the risk of developing the disease by combining information on family…
In the largest study of its kind to date, Cambridge researchers have looked at why some people manage to stay thin while others gain weight easily. They have found that the genetic dice are loaded in favour of thin people and against those at the obese end of the spectrum. More than six in ten adults in the UK are…
Previous work from KJ Patel’s group in the LMB’s PNAC Division revealed that aldehydes – such as acetaldehyde, a by-product of alcohol metabolism – can damage our DNA. Further research by the group showed that our cells are protected against these toxic aldehydes using a two-tier protection system: enzymes that remove these aldehydes (tier-1) and DNA repair that fixes the…
The work on evidence synthesis carried out by Daniela De Angelis and her team has contributed to the improvement of health care and overall public health by directly influencing policy in the area of HIV research. Their novel Multi-Parameter Evidence Synthesis (MPES) approach to estimating the HIV burden (De Angelis et al., 2014) has been, and continues to be, the chosen…
