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MRC Mitochondrial Biology Unit

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MBU

MRC Mitochondrial Biology Unit
Brief descriptionResearch at the MRC Mitochondrial Biology Unit is focussed on the involvement of mitochondria and their dysfunction in an ever-increasing range of human diseases, and even, perhaps, in the process of ageing. The Unit has three major scientific aims:

-To understand the fundamental processes taking place in mitochondria
-To understand the involvement of these processes in human diseases
-To exploit knowledge of these fundamental processes for the development of new therapies to treat human diseases
History/ backgroundThe Unit has evolved from the former MRC Dunn Human Nutrition Unit and builds on research conducted there over the past 10 years. Its formation by the MRC recognizes growing evidence for the involvement of mitochondria and their dysfunction in an ever-increasing range of human diseases, and even, perhaps, in the process of ageing.
Main fundersMedical Research Council (MRC)
DirectorProfessor Massimo Zeviani
Structure9 research groups work on 10 topics based on understanding the fundamental biochemical and biological processes which occur in mitochondria:

- ATP synthase
- Bacterial complex I
- Bioinformatics
- Mitochondrial carriers
- Mitochondrial complex I
- Mitochondrial dysfunction
- Mitochondrial genetics
- Mitochondrial medicine
- Proteomics

Staff - Substantial graduate student body of 40-50 members
- Various established scientists in all departments
Working with industryThe Unit is engaged in collaborations with pharmaceutical companies to exploit fundamental knowledge to generate new therapies. In the coming months, this will be strengthened when the Unit makes new appointments and introduces new research activities into the Unit.
LocationThe Unit is housed in the Wellcome Trust/MRC Building.

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